Eurycomalactone - CAS 23062-24-0

Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor (IC50 of 0.5 μM) . Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα.

NF-κB, Apoptosis, Anti-infection, Bcl-2 Family, Akt

Apoptosis, PI3K/Akt/mTOR signaling, NF-κB, Cytoskeletal Signaling, Microbiology/Virology

23038

0.9987

C19H24O6

348.39

[H][C@]1(C)[C@@]2([H])OC(=O)[C@]1([H])[C@]1(C)C(=O)C[C@@]3([H])C(C)=CC(=O)[C@@H](O)[C@]3(C)[C@@]1([H])[C@H]2O

-20°C

Ice Packs

Natural Product