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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol - CAS 2866299-06-9

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol - CAS 2866299-06-9

SKU:MF-0147764-01

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  • Bioactivity

    Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan derivative that serves as a payload in drug conjugates, exhibiting significant inhibitory activity against various tumor cell lines [1].

  • Target

    ADC Cytotoxin, Topoisomerase

  • Related Pathways

    Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

  • CAS Number

    2866299-06-9

  • Molecular Formula

    C30H28FN3O6

  • Molecular Weight

    545.56

  • SMILES

    N(C(=O)C12CC(O)(C1)C2)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound