Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol - CAS 2891774-71-1

Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45), a camptothecin derivative, demonstrates potent inhibitory effects on cell proliferation, exhibiting an IC 50 of 2.92 ng/mL against MDA-MB-468 cells. It is primarily utilized in cancer research [1].

Topoisomerase, ADC Cytotoxin

Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

2891774-71-1

C31H30FN3O6

559.58

C(N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6)(=O)C78CC(CO)(C7)C8

-20°C

Ice Packs

Small Compound