Exatecan Intermediate 5 - CAS 143655-70-3

Exatecan Intermediate 5 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I (topoisomerase I) inhibitor with an IC50 of 2.2 μM (0.975 μg/mL), utilized in cancer research. This intermediate is also employed in the production of Antibody-Drug Conjugates (ADCs) .

ADC Cytotoxin

Antibody-drug Conjugate/ADC Related

143655-70-3

C15H17FN2O3

292.31

O=C(NC1=CC(F)=C(C2=C1C(=O)C(NC(=O)C)CC2)C)C

-20°C

Ice Packs

Small Compound