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Exatecan Intermediate 6 - CAS 143655-58-7
Exatecan Intermediate 6 - CAS 143655-58-7
SKU:MF-0122409-01
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Product Details
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Bioactivity
Exatecan Intermediate 6 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL), utilized in cancer research. Additionally, Exatecan Intermediate 6 is employed in the preparation of Antibody-Drug Conjugates (ADCs) .
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Target
ADC Cytotoxin
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
143655-58-7
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Molecular Formula
C13H14FNO2
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Molecular Weight
235.25
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SMILES
O=C(NC1=CC(F)=C(C2=C1C(=O)CCC2)C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound