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Exatecan Intermediate 7 - CAS 182182-32-7

Exatecan Intermediate 7 - CAS 182182-32-7

MF-0122415-01

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Product Details

  • Bioactivity

    Exatecan Intermediate 7 is an intermediary in the production of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL), utilized in cancer research. This intermediate is also employed in the synthesis of Antibody-Drug Conjugates (ADCs) .

  • Target

    ADC Cytotoxin

  • Related Pathways

    Antibody-drug Conjugate/ADC Related

  • CAS Number

    182182-32-7

  • Molecular Formula

    C13H13FN2O3

  • Molecular Weight

    264.25

  • SMILES

    O=C1C=2C(=CC(F)=C(C2CCC1=NO)C)NC(=O)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound