Exatecan intermediate 9 - CAS 2290562-59-1

Exatecanintermediate 9 is an intermediate used in the synthesis of Exatecan. Exatecan (DX-8951) is a common toxin component in the preparation of Antibody-Drug Conjugates (ADC Cytotoxin) and also acts as an inhibitor of DNA topoisomerase I (topoisomerase I), with an inhibition concentration (IC50) of 2.2 μM.

ADC Cytotoxin

Antibody-drug Conjugate/ADC Related

2290562-59-1

C26H24FN3O5

477.48

N(C(C)=O)C1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

-20°C

Ice Packs

Small Compound