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Exatecan mesylate dihydrate - CAS 197720-53-9

Exatecan mesylate dihydrate - CAS 197720-53-9

SKU:MF-0156752-01

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  • Bioactivity

    Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].

  • Target

    ADC Cytotoxin, Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

  • CAS Number

    197658

  • Molecular Formula

    C25H30FN3O9S

  • Molecular Weight

    567.58

  • SMILES

    CS(=O)(O)=O.N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62.O.O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound