Exisulind - CAS 59973-80-7

Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG) . Exisulind exhibits antineoplastic activity in solid tumour and haematological cancer cell lines and is an inhibitor of tumour growth in rodent models of colon, prostate, bladder, mammary and lung cancer.

Apoptosis, mTOR, PKA

Apoptosis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling

59886

0.9808

C20H17FO4S

372.41

CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccc(cc1)S(C)(=O)=O

-20°C

Ice Packs

Small Compound