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EZH2-IN-22 - CAS 2766231-05-2
EZH2-IN-22 - CAS 2766231-05-2
SKU:MF-0112303-01
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Product Details
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Bioactivity
EZH2-IN-22 (example 92) is a potent EZH2 inhibitor, exhibiting IC50 values of <0.00051 μM for EZH2 (Y641N) and EZH2 (Y641F), and 0.00052 μM for EZH2 (wt) . Additionally, EZH2-IN-22 demonstrates antiproliferative activity.
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Target
Histone Methyltransferase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2766231-05-2
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Molecular Formula
C36H50N4O8
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Molecular Weight
666.8
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SMILES
C(=C\C(O)=O)\C(O)=O.N(CC)(C1=C(C)C(C(NCC2=C(C)C=C(C)NC2=O)=O)=CC(O[C@@H]3C[C@H](C3)N4CCCCC4)=C1)C5CCOCC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound