EZH2-IN-5 - CAS 1403258-69-4

EZH2-IN-5 is a highly effective inhibitor of EZH2, displaying remarkable potency against both wild-type and mutant Tyr641 EZH2, with IC50 values of 1.52 nM and 4.07 nM, respectively.

Others, Histone Methyltransferase

Chromatin/Epigenetic, Others

1403185

C26H37BrN4O2

517.512

CCN([C@H]1CC[C@@H](CC1)N(C)C)c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C |wU:3.2,wD:6.9,(,1.54,;;-1.33,-.77,;-2.67,,;-4,-.77,;-5.33,,;-5.33,1.54,;-4,2.31,;-2.67,1.54,;-6.67,2.31,;-8,1.54,;-6.67,3.85,;-1.33,-2.31,;-2.67,-3.08,;-2.67,-4.62,;-4,-5.39,;-1.33,-5.39,;,-4.62,;1.33,-5.39,;2.67,-4.62,;1.33,-6.93,;2.67,-7.7,;2.67,-9.24,;4,-10.01,;5.33,-9.24,;4,-11.55,;2.67,-12.32,;2.67,-13.86,;1.33,-11.55,;1.33,-10.01,;,-9.24,;,-3.08,;1.33,-2.31,)|

-20°C

Ice Packs

Small Compound