EZH2-IN-9 - CAS 2700897-24-9

EZH2-IN-9 is a potent inhibitor of EZH2, which, through overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations), causes abnormal elevations in H3K27me3 and contributes to the growth and development of various tumours (e.g., breast cancer, prostate cancer, leukaemia) . EZH2-IN-9 has shown potential for cancer research.

Histone Methyltransferase, Others

Chromatin/Epigenetic, Others

2700897-24-9

C28H32ClF2N3O5S

596.09

CC1=C2C(OC(C)(O2)[C@@H]3CC[C@@H](C(=O)N4CC(F)(F)C4)CC3)=C(Cl)C=C1C(NCC5=C(SC)C=C(C)NC5=O)=O

-20°C

Ice Packs

Small Compound