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Molfinity

F-1 - CAS 2244775-31-1

F-1 - CAS 2244775-31-1

MF-0015931-01

$60.08 USD
$60.08 USD
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Product Details

  • Bioactivity

    F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.

  • Target

    ROS Kinase, ALK, ROS

  • Related Pathways

    Tyrosine Kinase/Adaptors, Immunology/Inflammation, Angiogenesis

  • CAS Number

    2244743

  • Purity

    0.995

  • Molecular Formula

    C22H27ClN8O3S

  • Molecular Weight

    519.02

  • SMILES

    COc1nc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound