F5446 - CAS 2304465-89-0

F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor. It promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3 on the FAS promoter to increase Fas expression, while inhibiting CTL effector gene expression.

Histone Methyltransferase, Apoptosis

Apoptosis, Chromatin/Epigenetic

2304376

0.9856

C26H17ClN2O8S

552.94

COC(=O)c1cc2-c3c(c[nH]c3C(=O)C(=O)c2n1S(=O)(=O)c1ccc(Cl)cc1)C(=O)OCc1ccccc1

-20°C

Ice Packs

Small Compound