Fabomotizole dihydrochloride - CAS 189638-30-0

Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors.

Endogenous Metabolite, Others

Metabolism, Others

189608

C15H23Cl2N3O2S

380.33

Cl.Cl.CCOc1ccc2nc(SCCN3CCOCC3)[nH]c2c1

-20°C

Ice Packs

Small Compound