Factor D inhibitor 6 - CAS 1386455-51-1

Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.

Complement System, Others

Immunology/Inflammation, Others

1386403

C23H22ClFN6O3

484.92

[H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)N[C@H](C)c1cccc(Cl)c1F)C(=O)Cn1nc(C(N)=O)c2ccncc12

-20°C

Ice Packs

Small Compound