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FAK/aurora kinase-IN-1 - CAS 2178117-69-4

FAK/aurora kinase-IN-1 - CAS 2178117-69-4

MF-0147555-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].

  • Target

    Aurora Kinase, FAK

  • Related Pathways

    Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Chromatin/Epigenetic

  • CAS Number

    2178117-69-4

  • Molecular Formula

    C23H24ClN7O3

  • Molecular Weight

    481.93

  • SMILES

    C(C(N(C)C)=O)(=O)C1=C(NC2=NC(NC=3C=CC(=NC3)N4CCOCC4)=NC=C2Cl)C=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound