FAK-IN-20 - CAS 3004967-41-0

FAK-IN-20 (Compound 7b), a potent FAK inhibitor, demonstrates an IC 50 of 0.27 nM and exhibits anticancer properties. This compound arrests the cell cycle in the G2/M phase and induces cell apoptosis (apoptosis) through the generation of ROS [1].

FAK, Apoptosis

Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

3004967-41-0

C27H34ClN7O5S

604.12

N(C1=C(OC)C=C(NS(CCN2C[C@@H](C)O[C@@H](C)C2)(=O)=O)C=C1)C=3N=C(NC4=C(C(NC)=O)C=CC=C4)C(Cl)=CN3

-20°C

Ice Packs

Small Compound