FAK inhibitor 6 - CAS 2410056-27-6

Compound 26F effectively optimizes enzyme inhibition (IC50 = 28.2 nM) while demonstrating relatively low cytotoxicity (IC50 = 3.32 μM) . It induces apoptosis in MDA-MB-231 cells in a dose-dependent manner and efficiently arrests these cells in the G0/G1 phase.

Others, FAK

Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Others

2410023

C25H24FN5O2S

477.55

N(C=1N=C2C(=CSC2=CN1)C3=C(OC)C=CC=C3)C4=CC(F)=C(C(NC5CCNCC5)=O)C=C4

-20°C

Ice Packs

Small Compound