Falcarindiol - CAS 55297-87-5

Falcarindiol is an orally active natural polyacetylene compound exhibiting anti-inflammatory and antiproliferative properties. It inhibits NO production in LPS-induced mouse macrophages, reduces tyrosine phosphorylation of JAK1 and JAK2, and modulates STAT1 nuclear translocation, thereby suppressing iNOS expression.

JAK, STAT, NOD, NOS

Tyrosine Kinase/Adaptors, Immunology/Inflammation, Stem Cells, NF-κB, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis

55205

0.9938

C17H24O2

260.37

C([C@H](/C=C\CCCCCCC)O)#CC#C[C@H](C=C)O

-20°C

Ice Packs

Natural Product