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Falnidamol - CAS 196612-93-8

Falnidamol - CAS 196612-93-8

MF-0014138-01

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. It displays >1000-fold lower potency against ErbB2 (IC50=3.4 μM) and other related tyrosine kinases (IC50>10 μM) . Falnidamol is a pyrimido-pyrimidine compound and exhibits anti-cancer activity.

  • Target

    EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

  • CAS Number

    196511

  • Purity

    0.98816

  • Molecular Formula

    C18H19ClFN7

  • Molecular Weight

    387.84

  • SMILES

    CN1CCC(CC1)Nc1ncc2ncnc(Nc3ccc(F)c(Cl)c3)c2n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound