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Farrerol - CAS 24211-30-1
Farrerol - CAS 24211-30-1
SKU:MF-0012357-01
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Product Details
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Bioactivity
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that Farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases.
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Target
Akt, p38 MAPK, ERK
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Related Pathways
PI3K/Akt/mTOR signaling, MAPK, Cytoskeletal Signaling
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CAS Number
24211-30-1
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Purity
0.9996
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Molecular Formula
C17H16O5
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Molecular Weight
300.31
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SMILES
Cc1c(O)c(C)c2OC(CC(=O)c2c1O)c1ccc(O)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product