Fascaplysin chloride - CAS 114719-57-2

Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 μM) . Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.

Others, Autophagy, Reactive Oxygen Species, Apoptosis

Immunology/Inflammation, NF-κB, Others, Autophagy, Metabolism, Apoptosis

114660

C18H11ClN2O

306.75

[Cl-].O=C1C2=C(C=CC=C2)[N+]2=C1C1=C(C=C2)C2=CC=CC=C2N1

-20°C

Ice Packs

Natural Product