FD-211 - CAS 162341-24-4

FD-211 is a δ lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 μg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 μg/ml) . FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 μg/ml for all) .

Others

Others

162313

C13H16O4

236.267

[H][C@@]12O[C@H](\C=C\C)[C@H](O)C=C1C(=O)O[C@H]2\C=C\C |c:9|

-20°C

Ice Packs

Small Compound