FD-IN-1 - CAS 1646682-14-5

FD-IN-1 (Compound 12) is an orally active Factor D (FD) inhibitor (IC50=12 nM) that also inhibits Factor XIa (FXIa) and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.

Complement System, Factor Xa, Serine/threonin kinase

Metabolism, Immunology/Inflammation, Cell Cycle/Checkpoint

1646663

C23H23NO4

377.43

C(OC1=C(CC(O)=O)C=CC=C1)C=2C=C(C=CC2)C3=CC([C@@H](CO)N)=CC=C3

-20°C

Ice Packs

Small Compound