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FEN1-IN-6 - CAS 824983-84-8
FEN1-IN-6 - CAS 824983-84-8
SKU:MF-0157031-01
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Product Details
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Bioactivity
FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and also targets the related endonuclease xeroderma pigmentosum G (XPG) with an IC50 of 23 nM [1].
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Target
FLAP
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Related Pathways
Immunology/Inflammation
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CAS Number
824891
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Molecular Formula
C12H8N2O5S2
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Molecular Weight
324.33
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SMILES
S(=O)(=O)(C=1C2=C(SC1)C(=O)N(O)C(=O)N2)C3=CC=CC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound