FEN1-IN-7 - CAS 824983-90-6

FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells. Additionally, it targets the related endonuclease, xeroderma pigmentosum G (XPG), with an IC50 of 3.04 μM. FEN1-IN-7 enhances the sensitivity of cancer cells to potent DNA alkylating or methylating agents [1].

FLAP

Immunology/Inflammation

824887

C16H14N2O6S

362.36

C(N1C2=C(C(=O)N(O)C1=O)C(C)=CS2)C=3C=C4C(=C(OC)C3)OCO4

-20°C

Ice Packs

Small Compound