Fenspiride - CAS 5053-06-5

Fenspiride is an antagonist of H1-histamine receptors. Fenspiride is an orally active non-steroidal anti-inflammatory agent that can be used for the treatment of respiratory tract infections and otitis media. Fenspiride inhibited phosphodiesterase 4 and phosphodiesterase 3 activities with -logIC50 values of 4.16+/-0.09 and 3.44+/-0.12, respectively. Phosphodiesterase 5 activity was also inhibited with a -logIC50 value of approximately 3.8.

Others, PDE, Histamine Receptor

Immunology/Inflammation, Metabolism, GPCR/G Protein, Neuroscience, Others

5053-06-5

C15H20N2O2

260.33

O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1

-20°C

Ice Packs

Small Compound