Feralolide - CAS 149418-38-2

Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, respectively. It exhibits antioxidant properties, effectively inhibiting 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) . Research suggests feralolide's potential in studying cognitive disorders, including Alzheimer's disease, for its memory restoration and enhancement capabilities [1].

Others, Cholinesterase (ChE)

Neuroscience, Others

149378

C18H16O7

344.32

O=C1C=2C(C[C@@H](CC3=C(C(C)=O)C(O)=CC(O)=C3)O1)=CC(O)=CC2O

-20°C

Ice Packs

Natural Product