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Molfinity

FerroLOXIN-1 - CAS 2773428-48-9

FerroLOXIN-1 - CAS 2773428-48-9

MF-0112389-01

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Product Details

  • Bioactivity

    FerroLOXIN-1 is a potent inhibitor of 15LOX-2, selectively blocking the production of ferroptosis-promoting HOO-ETE-PE and preventing RSL3-induced ferroptosis (ferroptosis) . It interacts closely and specifically with 15LOX-2, particularly engaging with Y154, N155, and W158.

  • Target

    Ferroptosis, Lipoxygenase

  • Related Pathways

    Metabolism, Apoptosis

  • CAS Number

    2773371

  • Molecular Formula

    C23H16F5N3

  • Molecular Weight

    429.39

  • SMILES

    FC1=CC=CC(=C1)N2C=C(N=C2NCC3=CC=C(C(F)=C3)C(F)(F)F)C=4C=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound