Fezolamine - CAS 80410-36-2

Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytryptamine or [3H]dopamine in vitro. It blocked the inhibitory effects of rifampicin and tetraphenyl in classical behavioral tests using monoamine-depleted animals.

Others, Norepinephrine, 5-HT Receptor, Dopamine Receptor, Adrenergic Receptor

Others, Neuroscience, GPCR/G Protein

80372

0.9986

C20H23N3

305.42

C(CCN(C)C)N1C=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3

-20°C

Ice Packs

Small Compound