FGFR-IN-22 - CAS 1431872-18-2

FGFR-IN-22 (Compound 23) is an FGFR inhibitor with IC50 values of 0.631 nM for FGFR1, 1.26 nM for FGFR2, 0.851 nM for FGFR3, and 1 nM for FGFR4. It effectively inhibits cell proliferation dependent on FGFR1 and FGFR3 signaling pathways. FGFR-IN-22 is applicable in research related to cancers such as chronic lymphocytic leukemia (CLL) .

FGFR

Angiogenesis, Tyrosine Kinase/Adaptors

1431852

C23H21FN8O2

460.46

FC=1C(OC)=CC(OC)=CC1N(C2=NC3=NC(=CN=C3C=C2)C=4C=NN(C4)C)CC5=NC=CN5

-20°C

Ice Packs

Small Compound