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Molfinity

FGFR1 inhibitor-11 - CAS 2157482-40-9

FGFR1 inhibitor-11 - CAS 2157482-40-9

MF-0147570-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    FGFR1 inhibitor-11 (compound 5g) effectively targets and binds to FGFR1, subsequently inhibiting the downstream signaling pathways ERK1/2 and IκBα/NF-κB, which results in the suppression of RANKL-induced osteoclastogenesis. This compound also exhibits oral bioactivity [1].

  • Target

    FGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    2157482-40-9

  • Molecular Formula

    C23H18O4

  • Molecular Weight

    358.39

  • SMILES

    C(C1=C(OC=2C(C1=O)=CC=CC2)C3=CC=C(OC)C=C3)C4=C(O)C=CC=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound