FGFR4-IN-17 - CAS 3011805-61-8

FGFR4-IN-17 (Compound (S) -23), a piperazinyl diflurindan derivative featuring a pyridinyl group, functions as an inhibitor of FGFR. It exhibits IC 50 values of 24.2 nM for FGFR1, 16.1 nM for FGFR2, 78.0 nM for FGFR3, and 68.0 nM for FGFR4. Notably, FGFR4-IN-17 demonstrates significant antitumor activity [1].

FGFR

Tyrosine Kinase/Adaptors, Angiogenesis

3011805-61-8

C29H27F3N4O2

520.55

FC1(F)C=2C([C@H](C1)N3CCN(C)CC3)=CC=C(NC(=O)C4=CC(C#CC=5C=C(OC)C=NC5)=C(F)C=C4)C2

-20°C

Ice Packs

Small Compound