FGI-106 tetrahydrochloride - CAS 1149348-10-6

FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective concentrations (EC50s) of 100 nM, 800 nM, and 400-900 nM, respectively. Additionally, it effectively inhibits non-hemorrhagic fever viruses, notably HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively, indicating its broad-spectrum antiviral potential.

Influenza Virus, Anti-infection, HIV Protease, HCV Protease, Virus Protease

Microbiology/Virology, Proteases/Proteasome

1149332

0.9968

C28H42Cl4N6

604.48

Cl.Cl.Cl.Cl.CN(C)CCCNc1cc(C)nc2c1ccc1c2ccc2c(NCCCN(C)C)cc(C)nc12

-20°C

Ice Packs

Small Compound