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Molfinity

FGTI-2734 - CAS 1247018-19-4

FGTI-2734 - CAS 1247018-19-4

MF-0022298-01

$45.13 USD
$45.13 USD
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Product Details

  • Bioactivity

    FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localization of KRAS, addressing the issue of KRAS resistance and inhibiting the growth of mutant KRAS patient-derived pancreatic tumors.

  • Target

    Kras, Ras, Transferase

  • Related Pathways

    Metabolism, MAPK

  • CAS Number

    1246995

  • Purity

    0.9969

  • Molecular Formula

    C26H31FN6O2S

  • Molecular Weight

    510.63

  • SMILES

    Cn1cncc1CN(CCN(CC1CCCCC1)S(=O)(=O)c1ccccn1)c1ccc(cc1F)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound