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Fibrinogen γ-chain (117-133) - CAS 160927-63-9

Fibrinogen γ-chain (117-133) - CAS 160927-63-9

SKU:MF-0127442-01

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  • Bioactivity

    Fibrinogen γ-chain (117-133) is a selective inhibitor of intercellular adhesion molecule-1 (ICAM-1), with an IC50 of approximately 20-40 μg/mL. It can block fibrinogen-mediated adhesion of monocytes to endothelial cells and shows potential for research in thrombo-inflammatory diseases, such as atherosclerosis and organ transplant rejection.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    160927-63-9

  • Molecular Formula

    C84H147N25O27

  • Molecular Weight

    1939.22

  • SMILES

    [C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(N)=O)=O)CCC(N)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)C)=O)C(C)C)=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)[C@H](CC)C)=O)CCCCN

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide