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Fidarestat - CAS 136087-85-9
Fidarestat - CAS 136087-85-9
SKU:MF-0011955-01
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Product Details
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Bioactivity
Fidarestat (SNK 860), an aldose reductase inhibitor, exhibits IC50 values of 26 nM, 33 μM, and 1.8 μM against aldose reductase, AKR1B10, and V301L AKR1B10 respectively, demonstrating potential for diabetes treatment.
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Target
Reductase
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Related Pathways
Endocrinology/Hormones, Metabolism
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CAS Number
136087-85-9
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Molecular Formula
C12H10FN3O4
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Molecular Weight
279.22
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SMILES
O=C1[C@]2(C=3C(O[C@H](C(N)=O)C2)=CC=C(F)C3)NC(=O)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound