Filanesib TFA - CAS 1781834-99-8

Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing.

Kinesin, Others

Others, Cytoskeletal Signaling

1781727

C22H23F5N4O4S

534.5

C(C(O)=O)(F)(F)F.C(CCN)[C@@]1(N(C(N(OC)C)=O)N=C(S1)C2=C(F)C=CC(F)=C2)C3=CC=CC=C3

-20°C

Ice Packs

Small Compound