Filgotinib maleate - CAS 1802998-75-9

Filgotinib (maleate) is a selective, orally active JAK1 inhibitor that effectively inhibits the activity of JAK1 (IC50: 10 nM), JAK2 (IC50: 28 nM), JAK3 (IC50: 810 nM) and TYK2 (IC50: 116 nM) . maleate) can be used to study rheumatoid arthritis (RA) and Crohn's disease.

Others, HIV Protease, JAK

Chromatin/Epigenetic, Microbiology/Virology, Tyrosine Kinase/Adaptors, Others, Proteases/Proteasome, Stem Cells, Angiogenesis, JAK/STAT signaling

1802914

C25H27N5O7S

541.58

OC(=O)\C=C/C(O)=O.O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1

-20°C

Ice Packs

Small Compound