Fimepinostat - CAS 1339928-25-4

Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.

PI3K, Apoptosis, HDAC

PI3K/Akt/mTOR signaling, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic

1339928-25-4

0.9987

C23H24N8O4S

508.55

COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1

-20°C

Ice Packs

Small Compound