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Molfinity

Firategrast - CAS 402567-16-2

Firategrast - CAS 402567-16-2

SKU:MF-0015838-01

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  • Bioactivity

    Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist that reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity. It is used in relapsing-remitting multiple sclerosis, associated with modest reductions in CD4, CD8, and CD19 lymphocyte counts in cerebrospinal fluid.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    402549

  • Purity

    0.9967

  • Molecular Formula

    C27H27F2NO6

  • Molecular Weight

    499.5

  • SMILES

    CCOCc1cc(OC)c(c(OC)c1)-c1ccc(C[C@H](NC(=O)c2c(F)cccc2F)C(O)=O)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound