Firazorexton hydrate - CAS 2861934-86-1

Firazorexton hydrate (TAK-994) is a brain-penetrant, orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM, effectively reducing wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1].

OX Receptor, Others, ERK

Neuroscience, GPCR/G Protein, Others, MAPK

2861847

C22H25F3N2O4S.3/2H2O

497.53

C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O

-20°C

Ice Packs

Small Compound