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FKBP51-Hsp90-IN-2 - CAS 601511-07-3
FKBP51-Hsp90-IN-2 - CAS 601511-07-3
SKU:MF-0120626-01
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Product Details
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Bioactivity
FKBP51-Hsp90-IN-2 (Compound E08) functions as a selective inhibitor for the FKBP51 - Hsp90 protein-protein interaction, exhibiting IC 50 values of 0.4 μM for FKBP51 and 5 μM for FKBP52. Beyond its inhibitory actions, FKBP51-Hsp90-IN-2 enhances cellular energy metabolism and promotes neurite growth. This compound is utilized in the study of neurodegenerative diseases and cancer [1].
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Target
FKBP, HSP
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Related Pathways
Metabolism, Apoptosis, Autophagy, Cytoskeletal Signaling, Immunology/Inflammation
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CAS Number
601511-07-3
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Molecular Formula
C25H27N3O2S
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Molecular Weight
433.57
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SMILES
O=C(NC1=CC=C(NC(=O)CC)C(=C1)C)CSC2=NC3=CC4=C(C=C3C=C2C)CCC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound