Flavoglaucin - CAS 523-73-9

Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammatory effects, it shows inhibitory effects on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Flavoglaucin exhibits a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with theIC (50) value of 11.3 microM.

Nrf2, NF-κB, NOS, IL Receptor, Phosphatase, COX, Autophagy, Prostaglandin Receptor, TNF

Metabolism, Apoptosis, GPCR/G Protein, Immunology/Inflammation, Neuroscience, Autophagy, NF-κB

441

C19H28O3

304.42

CCCCCCCc1c(O)cc(CC=C(C)C)c(O)c1C=O

-20°C

Ice Packs

Natural Product