1 1

Molfinity

Flindokalner - CAS 187523-35-9

Flindokalner - CAS 187523-35-9

MF-0019521-01

$33.92 USD
$33.92 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. It is also a positive modulator of large conductance calcium-activated K channels (BKca) and displays negative modulatory activity at Kv7.1 channels (Ki = 3.7 μM) . Additionally, Flindokalner acts as a negative modulator of GABAA receptors and demonstrates anxiolytic efficacy in vivo.

  • Target

    Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    187479

  • Purity

    0.9996

  • Molecular Formula

    C16H10ClF4NO2

  • Molecular Weight

    359.7

  • SMILES

    COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound