Flonoltinib sulfate - CAS 2568842-57-7

Flonoltinib maleate is an orally active dual inhibitor of JAK2/FLT3, with IC50 values of 0.7 nM for JAK2, 4 nM for FLT3, 26 nM for JAK1, and 39 nM for JAK3. It exhibits anticancer properties.

Apoptosis, FLT, JAK

Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis, Stem Cells

2568778

C25H36FN7O5S

565.661

O=S(=O)(O)O.FC1=CC(=CC=C1N2CCC(N(C)CCO)CC2)NC=3N=CC(=C(N3)C=4C=NN(C4)C(C)C)C

-20°C

Ice Packs

Small Compound