FLT3/CDKs ligand-1 - CAS 2452019-67-7

FLT3/CDKs ligand-1 (Compound 14) functions as a ligand for target proteins, promoting the degradation of Cyclin-Dependent Kinases (CDK) and FMS-like tyrosine kinase 3 (FLT3), thereby inhibiting the proliferation and survival of leukemia cells associated with FLT3/CDK. This compound is also used in the synthesis of PROTAC FLT3/CDKs Degrader-1.

FLT, Ligands for Target Protein for PROTAC, CDK

PROTAC, Cell Cycle/Checkpoint, Angiogenesis, Tyrosine Kinase/Adaptors

2452019-67-7

C26H31N9O3

517.58

O=C(OC(C)(C)C)N1CCN(CC2=CC=C(C=C2)NC(=O)C3=NNC=C3NC=4N=CN=C5NC=CC54)CC1

-20°C

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PROTAC