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FLT3/D835Y-IN-1 - CAS 2648799-49-7

FLT3/D835Y-IN-1 - CAS 2648799-49-7

SKU:MF-0138246-01

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  • Bioactivity

    FLT3/D835Y-IN-1 (compound 13a) is an orally active, selective inhibitor of FLT3 and FLT3/D835Y with IC50 values of 0.26 nM and 0.18 nM, respectively. It exhibits anticancer efficacy and has research value in AML (acute myeloid leukemia) .

  • Target

    FLT, Others

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Others

  • CAS Number

    2648743

  • Molecular Formula

    C22H21N5O3

  • Molecular Weight

    403.43

  • SMILES

    O=C1\C(\C=2C(N1)=CC=CC2)=C/3\C(=N\OCC(=O)N4CCNCC4)\C=5C(N3)=CC=CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound