FLT3-IN-11 - CAS 2499966-50-4

FLT3-IN-11 (compound 30) is an orally active, potent, and selective inhibitor of FLT3 kinase that targets wild-type FLT3 (IC50: 7.22 nM) and FLT3-D835Y (IC50: 4.95 nM), demonstrating significant anti-AML effects with an IC50 value of 3.2 nM for MV4-11 cells.

Others, FLT

Tyrosine Kinase/Adaptors, Others, Angiogenesis

2499912

C20H25F3N6O

422.45

N(C=1C(C(F)(F)F)=CN=C(NC2=CC=C(C(N(C)C)=O)C=C2)N1)[C@@H]3CC[C@H](N)CC3

-20°C

Ice Packs

Small Compound